Which genomic technology allows for whole genome sequencing?

Prepare for the AMNH Genetic and Genomic in Nursing Exam. Explore our flashcards and multiple choice questions, each with hints and explanations. Ace your exam with confidence!

Next-generation sequencing (NGS) is the appropriate choice for whole genome sequencing because it is designed to rapidly sequence large volumes of DNA simultaneously. This technology utilizes massive parallel sequencing, which allows for the identification of variations across the entire genome in a very cost-effective and time-efficient manner, making it ideal for comprehensive genomic studies.

NGS can process millions of DNA fragments concurrently, leading to the generation of vast amounts of sequence data in a relatively short time. This contrasts with other techniques. For instance, Sanger sequencing is generally used for sequencing smaller DNA fragments or for validating specific regions; it does not have the capacity to efficiently sequence entire genomes on a large scale. Similarly, polymerase chain reaction (PCR) is a technique used primarily to amplify DNA segments, not to sequence entire genomes. Microarray analysis is used to study gene expression or to detect specific mutations and does not provide the full sequence of the genome.

Therefore, the ability of NGS to perform whole genome sequencing sets it apart as the correct answer in this context.

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